Small Pet Health
Rat Respiratory Infection — UK Vet Guide
Published Last updated 3 min read
Quick answer
Most pet rats carry Mycoplasma pulmonis, and stress or dirty bedding can tip it into active respiratory infection. Sneezing, porphyrin (red) staining around the eyes and nose, and rattly breathing mean it's time for the vet. Laboured breathing is a same-day emergency.
Key takeaways
- Usually not. It's porphyrin — a red secretion from a gland behind the eye that dries to look like blood. Small traces after sleep are normal, but heavy staining with sneezing suggests illness or stress.
- New rats often sneeze for a few days while adjusting to unfamiliar smells — the 'new home sneezes'. Persistent sneezing, clicking or rattling breathing, or porphyrin staining needs a vet.
- Mycoplasma itself is usually carried for life, but your vet can control flare-ups with prescription antibiotics and supportive care. Good husbandry keeps most rats comfortable between episodes.
Mycoplasma: why rats are so prone
Respiratory disease is the most common health problem in pet rats. The underlying cause is usually _Mycoplasma pulmonis_, a bacterium carried silently by most pet rats, often passed from mother to pup. It flares into active illness when the immune system is weakened by:
- Ammonia from dirty cages — urine build-up damages the airways
- Dusty or unsuitable bedding — UK rat care guides warn against cedar and pine
- Poor ventilation, overcrowding and stress
- Other infections taking hold at the same time
Once active, infection typically moves from the nose and middle ear down into the lungs — pneumonia can follow quickly.
Symptoms
| Sign | What you see |
|---|---|
| Sneezing | Persistent or frequent — more than the occasional 'new home sneezes' |
| Porphyrin staining | Red, blood-like discharge around eyes and nose |
| Noisy breathing | Clicking, rattling or wheezing sounds |
| Laboured breathing | Sides heaving, stretched posture — emergency |
| Rough coat | Fur puffed or staring; hunched posture |
| Lethargy | Sleeping more, less interest in food, weight loss |
| Head tilt | Circling or tilt if infection reaches the inner ear |
Porphyrin is not blood — it's a red secretion from the Harderian gland behind the eye, produced under stress and illness. Heavy staining alongside other signs means something is wrong.
When to see the vet
Book a prompt appointment for persistent sneezing, porphyrin staining or audible breathing — early treatment stops lung damage.
Treat as a same-day emergency if your rat has laboured or open-mouth breathing, blue-tinged ears or tail, or sits hunched, fluffed and unresponsive. Rats decline fast once the lungs are involved.
What the vet will do
Respiratory infections are treated with prescription antibiotics chosen by your vet, often alongside anti-inflammatories and nursing care. There are no safe over-the-counter substitutes, and doses must be calculated for a tiny body weight — never attempt to dose antibiotics yourself.
Be prepared for a managed condition rather than a one-off cure: mycoplasma is rarely eliminated completely, so flare-ups can recur under stress. Many rats live comfortably for their normal lifespan with prompt treatment each time.
Prevention and husbandry
- Clean little and often — spot-clean wet bedding daily to control ammonia; full clean regularly
- Dust-free paper bedding — avoid cedar and pine, which irritate airways
- Good ventilation without draughts
- Don't overcrowd — follow your cage's space guidance for the number of rats
- Quarantine new rats for at least two weeks before introducing them
- Feed a complete diet — good nutrition supports the immune system
- Handle and health-check daily — listen to breathing; you'll catch flare-ups early
For everyday housing, diet and companionship, see Rat care UK.
Sources & further reading
Facts in this guide are rewritten in plain English from publicly available UK advice. We name the organisation where a specific point comes from their guidance. Links below go to the original pages — use them to read the source material directly.
PETHEALTH+ is independent. These organisations do not sponsor, approve, or partner with this website. Guidance checked against sources listed below (last updated 2026-07-18).
- Rat Care in the UK — Diet, Housing & Health
- Mouse Care in the UK — Housing, Diet & Health
- Gerbil Care in the UK
- Ferret Adrenal Disease — UK Vet Guide
- Ferret Care in the UK
- Guinea Pig Bloat — UK Emergency Guide
- Guinea Pig Care in the UK
- Guinea Pig Heatstroke UK
Also see symptoms, symptom checker, and poison guide.
Frequently Asked Questions
- Is the red stuff around my rat's eyes blood?
- Usually not. It's porphyrin — a red secretion from a gland behind the eye that dries to look like blood. Small traces after sleep are normal, but heavy staining with sneezing suggests illness or stress.
- Why is my rat sneezing?
- New rats often sneeze for a few days while adjusting to unfamiliar smells — the 'new home sneezes'. Persistent sneezing, clicking or rattling breathing, or porphyrin staining needs a vet.
- Can rat respiratory infections be cured?
- Mycoplasma itself is usually carried for life, but your vet can control flare-ups with prescription antibiotics and supportive care. Good husbandry keeps most rats comfortable between episodes.
- Is it contagious to my other rats?
- Respiratory infections spread readily between rats through close contact and shared air. Quarantine new rats for at least two weeks, and ask your vet whether companions also need treatment.
- When is sneezing an emergency?
- Laboured, noisy or open-mouth breathing, blue-tinged ears or tail, or a rat sitting hunched and fluffed up needs a same-day vet appointment.